Weight Loss That Actually Works.
Physician-directed Tirzepatide programs at Plump Medical Spa — now including a daily oral chewable option. Designed around your biology — not a one-size-fits-all protocol. Monitored, adjusted, and overseen by Dr. Amir Mortazavi, MD from start to finish.
Why Plump Uses Tirzepatide — Not Semaglutide
Most weight loss programs in Orange County use semaglutide (Ozempic, Wegovy). At Plump, Dr. Mortazavi made a deliberate clinical decision to use Tirzepatide (Mounjaro, Zepbound) exclusively — and the evidence supports it.
Tirzepatide is a dual GLP-1/GIP receptor agonist. GLP-1 controls appetite and insulin. GIP adds fat metabolism and a more favorable side effect profile. Clinical trials show Tirzepatide produces greater average weight loss than semaglutide — up to 20–22% of body weight — with improved tolerability for many patients.
New: Oral Chewable Tirzepatide
Plump Medical Spa now offers a liposomal oral chewable formulation of Tirzepatide — a once-daily alternative to the standard weekly injection, prepared through our partnered compounding pharmacy and dispensed only after physician review at consultation.
This option is designed for two specific groups: patients beginning GLP-1 therapy who prefer to start with a daily, non-injectable approach, and patients who have already reached their goal weight on injectable Tirzepatide and are transitioning to a long-term maintenance plan.
Physician-reviewed, pharmacy-coordinated. Every oral chewable prescription is reviewed by Dr. Mortazavi and coordinated directly with our partnered compounding pharmacy — the same medical oversight applied to every program at Plump. This is not a self-directed or online-only option. Individual results and tolerability vary; suitability is confirmed at consultation.
What GLP-1 Medications Do
Tirzepatide works by mimicking hormones your body naturally produces after eating. It signals fullness to your brain, slows gastric emptying, stabilizes blood sugar, and reduces appetite — making it significantly easier to eat less without feeling deprived.
Programs & Pricing
All programs are physician-directed by Dr. Mortazavi. Dosing is individualized at consultation and adjusted based on response and tolerability — not a fixed protocol applied to every patient.
Injectable Tirzepatide
Oral Chewable Tirzepatide (3mg)
GLP-1 Microdosing Program also available — $750 for 90 days. A physician-directed sub-therapeutic dosing protocol for patients focused on metabolic optimization, weight maintenance, or who have experienced side effects at standard doses.
Vitamin B12 & Folic Acid injections — $75. Energy and metabolism support available as a standalone or complement to any weight loss program.
How It Works at Plump
Who This Is For
Tirzepatide programs at Plump — both injectable and oral chewable — are appropriate for adults who have struggled to lose weight through diet and exercise alone, have weight-related health concerns, or are seeking a sustainable long-term approach rather than a short-term fix. A consultation with Dr. Mortazavi determines which format and dose is clinically appropriate for you.
This is not appropriate for patients who are pregnant, have a personal or family history of medullary thyroid carcinoma or MEN 2, or have certain pancreatic conditions. Full medical history review at consultation.
Physician-Directed — Not Telehealth
Every weight loss patient at Plump is evaluated and monitored personally by Dr. Mortazavi — including patients choosing the oral chewable option. This is not a telehealth prescription service. No online questionnaires, no automated refills, no remote oversight. Plump's approach integrates weight management with the broader aesthetic and longevity medicine context that makes it uniquely suited to address body composition and facial appearance together.
Frequently Asked Questions
What is the new oral chewable Tirzepatide option?
It's a 3mg liposomal chewable formulation of Tirzepatide, taken once daily instead of injected weekly. It's prepared through our partnered compounding pharmacy and prescribed only after physician review at consultation. It's a good option for patients starting GLP-1 therapy who prefer a daily non-injectable approach, or patients transitioning to long-term maintenance after reaching their goal weight.
Is the oral chewable as effective as injectable Tirzepatide?
The two formats work through the same mechanism but are dosed differently, and individual response varies. Dr. Mortazavi will help determine which format fits your goals, tolerance, and whether you're starting treatment or maintaining results — this is assessed and discussed at consultation rather than assumed.
Do you offer semaglutide (Ozempic or Wegovy) at Plump?
No. Plump Medical Spa uses Tirzepatide exclusively — not semaglutide. Dr. Mortazavi made this clinical decision based on evidence showing Tirzepatide produces greater average weight loss with a more favorable tolerability profile due to its dual GLP-1/GIP mechanism.
How quickly will I lose weight on Tirzepatide?
Most patients begin to notice appetite reduction within the first 1 to 2 weeks. Meaningful weight loss typically becomes visible at 4 to 8 weeks. Clinical trials show average weight loss of 15 to 22% of body weight over 72 weeks. Individual results vary based on dose, format, adherence, and metabolic factors.
What is the GLP-1 Microdosing Program?
The 90-day GLP-1 microdosing program uses sub-therapeutic doses for patients who want the metabolic and appetite-regulating benefits of GLP-1 without the full weight-loss dosing side effect profile. It is appropriate for weight maintenance, metabolic optimization, or patients who experienced side effects at standard doses. The full 90-day program is $750.
What is "Ozempic face" and can Plump address it?
Rapid weight loss from GLP-1 medications can cause significant facial volume loss — gaunt appearance, hollowed cheeks, and loss of jawline definition commonly referred to as "Ozempic face." Plump is one of the only practices combining GLP-1 prescribing and aesthetic medicine, offering a Facial Volume Loss Assessment ($350) for GLP-1 patients to proactively map and restore volume with Sculptra or dermal fillers before loss becomes visually significant.
Is financing available for the weight loss program?
Yes. Cherry and CareCredit financing are both accepted at Plump Medical Spa. Apply at pay.withcherry.com/plumpmedicalspa or carecredit.com/go/674KNF.
Do you serve patients from Irvine, Costa Mesa, and Huntington Beach?
Yes. Plump Medical Spa is located at 4667 MacArthur Blvd, Suite 310, Newport Beach — 10 to 20 minutes from Irvine, Costa Mesa, Laguna Beach, Huntington Beach, and Corona del Mar. Appointments are available Tuesday through Saturday, 10am to 6pm.
Ready to Start?
Book a consultation with Dr. Mortazavi to discuss whether injectable or oral chewable Tirzepatide is right for you.
4667 MacArthur Blvd, Suite 310 — Newport Beach, CA 92660
(949) 568-7544 — info@plumpmedicalspa.com
Tuesday – Saturday, 10am – 6pm